Long Haul Covid
- Sam the Centipede
- Posts: 2181
- Joined: Thu Feb 25, 2021 12:19 pm
Re: Long Haul Covid
Just spotted this from a week or two back, in The Guardian: Could microclots help explain the mystery of long Covid?
The title is a fair summary of the article. The author is a researcher at a university in South Africa. She suggests that microscopic blood clots could be a key component in (some? most?) cases of Long Covid. From the start it has been clear that SARS-CoV-2 can cause severe or mild blood clotting, and also that it can mess up the immune system's control signals and hence cause aberrant responses. Of course, blood clotting is a function of the immune system - the immune system ties in damage repair with its headline role in fighting infection.
It's worth a read for those who are interested. It supports my prediction that the importance of Long Covid will lead to many new insights, also improving treatments for other chronic conditions, such as CFS/ME.
The title is a fair summary of the article. The author is a researcher at a university in South Africa. She suggests that microscopic blood clots could be a key component in (some? most?) cases of Long Covid. From the start it has been clear that SARS-CoV-2 can cause severe or mild blood clotting, and also that it can mess up the immune system's control signals and hence cause aberrant responses. Of course, blood clotting is a function of the immune system - the immune system ties in damage repair with its headline role in fighting infection.
It's worth a read for those who are interested. It supports my prediction that the importance of Long Covid will lead to many new insights, also improving treatments for other chronic conditions, such as CFS/ME.
Re: Long Haul Covid
https://www.washingtonpost.com/health/2 ... -longterm/
I have a friend, fully vaxxed, who is going through this right now.Five months after being infected with the coronavirus, Nicole Murphy’s pulse rate is going berserk. Normally in the 70s, which is ideal, it has been jumping to 160, 170 and sometimes 210 beats per minute even when she is at rest — putting her at risk of a heart attack, heart failure or stroke.
No one seems to be able to pinpoint why. She’s only 44, never had heart issues, and when a cardiologist near her hometown of Wellsville, Ohio, ran all of the standard tests, “he literally threw up his hands when he saw the results,” she recalled. Her blood pressure was perfect, there were no signs of clogged arteries, and her heart was expanding and contracting well.
Murphy’s boomeranging heart rate is one of a number of mysterious conditions afflicting Americans weeks or months after coronavirus infections that suggest the potential of a looming cardiac crisis.
A pivotal study that looked at health records of more than 153,000 U.S. veterans published this month in Nature Medicine found that their risk of cardiovascular disease of all types increased substantially in the year following infection, even when they had mild cases. The population studied was mostly White and male, but the patterns held even when the researchers analyzed women and people of color separately. When experts factor in the heart damage probably suffered by people who put off medical care, more sedentary lifestyles and eating changes, not to mention the stress of the pandemic, they estimate there may be millions of new onset cardiac cases related to the virus, plus a worsening of disease for many already affected.
"Choose your leaders with wisdom and forethought. To be led by a coward is to be controlled by all that the coward fears… To be led by a liar is to ask to be told lies." -Octavia E. Butler
- Phoenix520
- Posts: 4151
- Joined: Mon Feb 22, 2021 1:20 pm
- Verified: ✅
Re: Long Haul Covid
I’ve had a couple of really short episodes of that. Really short, less than 1 minute. Wonder if they’re indicators?
Re: Long Haul Covid
I'm hardly an expert, but with my friend it was part and parcel of her case from the beginning.Phoenix520 wrote: ↑Mon Feb 21, 2022 5:19 pm I’ve had a couple of really short episodes of that. Really short, less than 1 minute. Wonder if they’re indicators?
"Choose your leaders with wisdom and forethought. To be led by a coward is to be controlled by all that the coward fears… To be led by a liar is to ask to be told lies." -Octavia E. Butler
Re: Long Haul Covid
I'm heading to the hospital tomorrow for some xrays. Blood work Monday. It's a good thing.
She gave me a prescription to help with the pain, and it is, and ordered a gazillion tests. I don't know if anything can help me, but I'm grateful that I'm finally being heard.
She gave me a prescription to help with the pain, and it is, and ordered a gazillion tests. I don't know if anything can help me, but I'm grateful that I'm finally being heard.
You can't wait until life isn't hard anymore before you decide to be happy.
Re: Long Haul Covid
Sorry to bother you again, but there is evidence that Eptein-Barr is related to long covid.
Coronavirus disease 2019 (COVID-19) patients sometimes experience long-term symptoms following resolution of acute disease, including fatigue, brain fog, and rashes. Collectively these have become known as long COVID. Our aim was to first determine long COVID prevalence in 185 randomly surveyed COVID-19 patients and, subsequently, to determine if there was an association between occurrence of long COVID symptoms and reactivation of Epstein–Barr virus (EBV) in 68 COVID-19 patients recruited from those surveyed. We found the prevalence of long COVID symptoms to be 30.3% (56/185), which included 4 initially asymptomatic COVID-19 patients who later developed long COVID symptoms. Next, we found that 66.7% (20/30) of long COVID subjects versus 10% (2/20) of control subjects in our primary study group were positive for EBV reactivation based on positive titers for EBV early antigen-diffuse (EA-D) IgG or EBV viral capsid antigen (VCA) IgM. The difference was significant (p < 0.001, Fisher’s exact test). A similar ratio was observed in a secondary group of 18 subjects 21–90 days after testing positive for COVID-19, indicating reactivation may occur soon after or concurrently with COVID-19 infection. These findings suggest that many long COVID symptoms may not be a direct result of the SARS-CoV-2 virus but may be the result of COVID-19 inflammation-induced EBV reactivation.
Coronavirus disease 2019 (COVID-19) patients sometimes experience long-term symptoms following resolution of acute disease, including fatigue, brain fog, and rashes. Collectively these have become known as long COVID. Our aim was to first determine long COVID prevalence in 185 randomly surveyed COVID-19 patients and, subsequently, to determine if there was an association between occurrence of long COVID symptoms and reactivation of Epstein–Barr virus (EBV) in 68 COVID-19 patients recruited from those surveyed. We found the prevalence of long COVID symptoms to be 30.3% (56/185), which included 4 initially asymptomatic COVID-19 patients who later developed long COVID symptoms. Next, we found that 66.7% (20/30) of long COVID subjects versus 10% (2/20) of control subjects in our primary study group were positive for EBV reactivation based on positive titers for EBV early antigen-diffuse (EA-D) IgG or EBV viral capsid antigen (VCA) IgM. The difference was significant (p < 0.001, Fisher’s exact test). A similar ratio was observed in a secondary group of 18 subjects 21–90 days after testing positive for COVID-19, indicating reactivation may occur soon after or concurrently with COVID-19 infection. These findings suggest that many long COVID symptoms may not be a direct result of the SARS-CoV-2 virus but may be the result of COVID-19 inflammation-induced EBV reactivation.
You can't wait until life isn't hard anymore before you decide to be happy.
- keith
- Posts: 4304
- Joined: Mon Feb 22, 2021 10:23 pm
- Location: The Swamp in Victorian Oz
- Occupation: Retired Computer Systems Analyst Project Manager Super Coder
- Verified: ✅lunatic
Re: Long Haul Covid
This is one of those times when i really dont want to be right.
When the pandemic started, my neice was an early victim. She was pretty bad but recovered.
She complained about headaches, but they were hoping they would go away soon. They were more worried about her heart and kidneys.
I said then that this thing was going to put people into the medical system for years. American health system is not equiped to deal with this level of cronic shit.
(I dont' know her current state, havent talked to her for a while. Ill have to catch up.)
When the pandemic started, my neice was an early victim. She was pretty bad but recovered.
She complained about headaches, but they were hoping they would go away soon. They were more worried about her heart and kidneys.
I said then that this thing was going to put people into the medical system for years. American health system is not equiped to deal with this level of cronic shit.
(I dont' know her current state, havent talked to her for a while. Ill have to catch up.)
Be assured that a walk through the ocean of most souls Would scarcely get your feet wet
Re: Long Haul Covid
Lani--
"Choose your leaders with wisdom and forethought. To be led by a coward is to be controlled by all that the coward fears… To be led by a liar is to ask to be told lies." -Octavia E. Butler
Re: Long Haul Covid
(and Sugar, too. )
Off Topic
I am barely keeping up with posts here, my job has gotten pretty intense lately, so not much free time. But I hope everyone is doing well. I'm totally stressed, overwhelmed with work and trying to get packed up to move closer to Mom.
"It actually doesn't take much to be considered a difficult woman. That's why there are so many of us."
--Jane Goodall
--Jane Goodall
Re: Long Haul Covid
RVInitRVInit wrote: ↑Fri Mar 18, 2022 12:20 pm
(and Sugar, too. )
Off TopicI am barely keeping up with posts here, my job has gotten pretty intense lately, so not much free time. But I hope everyone is doing well. I'm totally stressed, overwhelmed with work and trying to get packed up to move closer to Mom.
"Choose your leaders with wisdom and forethought. To be led by a coward is to be controlled by all that the coward fears… To be led by a liar is to ask to be told lies." -Octavia E. Butler
- Phoenix520
- Posts: 4151
- Joined: Mon Feb 22, 2021 1:20 pm
- Verified: ✅
Re: Long Haul Covid
While I don’t want to live where you live, at times I wish I were closer to all y’all are physically to be able yo do more than sends tots and pears when you need help.
Re: Long Haul Covid
Interesting meeting yesterday about long covid, A doctor told me that the NIH is close to ignoring the condition. Limited money, limited doctors & researchers. When I looked up info in the US, yep. There are studies, but they are based on 2000-early 2021. They usually refer to inflammation as the cause and claim that long haul usually lasts 3 to 6 months. UK info is a bit different and more recent data. There are articles about people still having long covid 18 months later.
Newer research indicates that the bloodstream may spread the virus throughout the body, including the brain, ocular tissue, muscles, skin, peripheral nerves, as well as tissue in the cardiovascular, gastrointestinal, reproductive, endocrine and lymphoid systems. So some people, like me, initially believe that they are recovering, but then weird things happen over time with new or worsening problems. Other people fully recover, then get hit with long covid 3 or more months later. Tricky little virus, isn't it. Also, there are 200 symptoms of long covid.
Newer research indicates that the bloodstream may spread the virus throughout the body, including the brain, ocular tissue, muscles, skin, peripheral nerves, as well as tissue in the cardiovascular, gastrointestinal, reproductive, endocrine and lymphoid systems. So some people, like me, initially believe that they are recovering, but then weird things happen over time with new or worsening problems. Other people fully recover, then get hit with long covid 3 or more months later. Tricky little virus, isn't it. Also, there are 200 symptoms of long covid.
You can't wait until life isn't hard anymore before you decide to be happy.
- Sam the Centipede
- Posts: 2181
- Joined: Thu Feb 25, 2021 12:19 pm
Re: Long Haul Covid
Thanks Lani. I appreciate your updates on these issues.
Viruses are tricksy little beasts! As you say, they can spread around the body, and some (including SARS-CoV-2) can persist in places that the immune system has limited access to, such as the retina of the eyes, testes, brain.
The amount of science we read about viruses tends to mask (in my view) just how difficult they are to study and how many unknown unknowns remain.
I wonder if more cold etc. viruses persist undetected in one's body and reactivate when immunity has subsided? I occasionally had cold symptoms when fully locked down, seeing nobody, wearing masks, distancing when out, etc. I couldn't identify any opportunities I had had to be interested, yet I was sneezing. What did that virus come from?
"Long Covid" is a large umbrella! Even if the NIH isn't doing much, there is plenty of research happening worldwide, so knowledge can only grow.
Viruses are tricksy little beasts! As you say, they can spread around the body, and some (including SARS-CoV-2) can persist in places that the immune system has limited access to, such as the retina of the eyes, testes, brain.
The amount of science we read about viruses tends to mask (in my view) just how difficult they are to study and how many unknown unknowns remain.
I wonder if more cold etc. viruses persist undetected in one's body and reactivate when immunity has subsided? I occasionally had cold symptoms when fully locked down, seeing nobody, wearing masks, distancing when out, etc. I couldn't identify any opportunities I had had to be interested, yet I was sneezing. What did that virus come from?
"Long Covid" is a large umbrella! Even if the NIH isn't doing much, there is plenty of research happening worldwide, so knowledge can only grow.
- Foggy
- Dick Tater
- Posts: 11071
- Joined: Mon Feb 22, 2021 8:45 am
- Location: Fogbow HQ
- Occupation: Dick Tater/Space Cadet
- Verified: grumpy ol' geezer
Re: Long Haul Covid
I'm just glad you found a little relief, Lani.
I'm Foggy and I forget if I approved this message.
- Tiredretiredlawyer
- Posts: 8068
- Joined: Tue Feb 23, 2021 10:07 pm
- Location: Rescue Pets Land
- Occupation: 21st Century Suffragist
- Verified: ✅🐴🐎🦄🌻5000 posts and counting
Re: Long Haul Covid
Drugs that work!!! Hooray, Lani!!!!!!
"Mickey Mouse and I grew up together." - Ruthie Tompson, Disney animation checker and scene planner and one of the first women to become a member of the International Photographers Union in 1952.
Re: Long Haul Covid
Happy for you, Lani!
"Choose your leaders with wisdom and forethought. To be led by a coward is to be controlled by all that the coward fears… To be led by a liar is to ask to be told lies." -Octavia E. Butler
Re: Long Haul Covid
I'm having trouble with double vision.Sam the Centipede wrote: ↑Wed Mar 23, 2022 8:20 am Thanks Lani. I appreciate your updates on these issues.
Viruses are tricksy little beasts! As you say, they can spread around the body, and some (including SARS-CoV-2) can persist in places that the immune system has limited access to, such as the retina of the eyes, testes, brain.
I planned to retire a few years ago, but with everything going on with me, I expect to retire sooner.
You can't wait until life isn't hard anymore before you decide to be happy.
- Sam the Centipede
- Posts: 2181
- Joined: Thu Feb 25, 2021 12:19 pm
Re: Long Haul Covid
Sorry to hear that, double vision is annoying (my eyes don't coordinate but my brain copes because it's hard years to get used to it). If the virus has affected your oculomotor nerves (the one that rotate the eyeball), that would cause double vision.Lani wrote: ↑Sun Mar 27, 2022 4:49 amI'm having trouble with double vision.Sam the Centipede wrote: ↑Wed Mar 23, 2022 8:20 am Thanks Lani. I appreciate your updates on these issues.
Viruses are tricksy little beasts! As you say, they can spread around the body, and some (including SARS-CoV-2) can persist in places that the immune system has limited access to, such as the retina of the eyes, testes, brain.
I planned to retire a few years ago, but with everything going on with me, I expect to retire sooner.
I hope it gets better for you, and that it isn't too frustrating.
- Phoenix520
- Posts: 4151
- Joined: Mon Feb 22, 2021 1:20 pm
- Verified: ✅
Re: Long Haul Covid
I started losing gobs of hair last week, apparently a long haul COVID effect. Supposedly it will start to grow back in a couple of months. In the grand scheme of things it’s no big deal but I’ve always had a lot of hair and it’s disconcerting to have it just leave my head for no discernable reason. Yes, I’m still vain after all these years.
Re: Long Haul Covid
I'd also find that very upsetting, and I do not have lots of hair. It's thin and fine, so would probably be gone quickly.
"Choose your leaders with wisdom and forethought. To be led by a coward is to be controlled by all that the coward fears… To be led by a liar is to ask to be told lies." -Octavia E. Butler
- Kriselda Gray
- Posts: 3125
- Joined: Sun Nov 28, 2021 10:48 pm
- Location: Asgard
- Occupation: Aspiring Novelist
- Verified: ✅
- Contact: