Fogbow

AndyinPA wrote: ↑Wed Oct 13, 2021 8:39 pm I heard today that Pennsylvania is 70 percent with two jabs. I don't know what the number is for just one jab, but it's got to be a good bit higher. Not bad.

AndyinPA wrote: ↑Wed Oct 13, 2021 8:39 pm I heard today that Pennsylvania is 70 percent with two jabs. I don't know what the number is for just one jab, but it's got to be a good bit higher. Not bad.

raison de arizona wrote: ↑Wed Oct 13, 2021 8:48 pm

AndyinPA wrote: ↑Wed Oct 13, 2021 8:39 pm I heard today that Pennsylvania is 70 percent with two jabs. I don't know what the number is for just one jab, but it's got to be a good bit higher. Not bad.

Go Arizona! You want to know who has a lower vax rate for the total population than Florida (58.5%)? Arizona! That's who!

You want to know who has a lower vax rate than Texas (52.2%)? Right again! Arizona! That's who!

Anyway. 52.0%. Blech. Half infectious.

Frater I*I wrote: ↑Wed Oct 13, 2021 8:48 pm

AndyinPA wrote: ↑Wed Oct 13, 2021 8:39 pm I heard today that Pennsylvania is 70 percent with two jabs. I don't know what the number is for just one jab, but it's got to be a good bit higher. Not bad.

I'd take bets that Pennsyltucky probably has a far lower percentage...hell if they could they'd try and make it a negative number....


I'll see myself out...

AndyinPA wrote: ↑Wed Oct 13, 2021 8:52 pm

Frater I*I wrote: ↑Wed Oct 13, 2021 8:48 pm

AndyinPA wrote: ↑Wed Oct 13, 2021 8:39 pm I heard today that Pennsylvania is 70 percent with two jabs. I don't know what the number is for just one jab, but it's got to be a good bit higher. Not bad.

I'd take bets that Pennsyltucky probably has a far lower percentage...hell if they could they'd try and make it a negative number....


I'll see myself out...

Not takin' that bet.

pipistrelle wrote: ↑Wed Oct 13, 2021 11:14 pm

AndyinPA wrote: ↑Wed Oct 13, 2021 8:52 pm

Frater I*I wrote: ↑Wed Oct 13, 2021 8:48 pm

I'd take bets that Pennsyltucky probably has a far lower percentage...hell if they could they'd try and make it a negative number....


I'll see myself out...

Not takin' that bet.

Some Trumpies I know in PA all got shots as soon as they could. They may be gullible but aren’t stupid.

scirreeve wrote: ↑Thu Oct 14, 2021 12:27 am These vax numbers don't mean anything without posting the definition. Some States post the % of those vaxxed 18+, others 12+, and others as % of total population. Hard to compare the numbers without knowing the definition. Rant over.

AndyinPA wrote: ↑Thu Oct 14, 2021 12:15 am

pipistrelle wrote: ↑Wed Oct 13, 2021 11:14 pm

AndyinPA wrote: ↑Wed Oct 13, 2021 8:52 pm

Not takin' that bet.

Some Trumpies I know in PA all got shots as soon as they could. They may be gullible but aren’t stupid.

I know more than a few trumpies here who got it, too, but I don't live in the Tucky part of the state.

pipistrelle wrote: ↑Thu Oct 14, 2021 2:50 pm

AndyinPA wrote: ↑Thu Oct 14, 2021 12:15 am

pipistrelle wrote: ↑Wed Oct 13, 2021 11:14 pm
Some Trumpies I know in PA all got shots as soon as they could. They may be gullible but aren’t stupid.

I know more than a few trumpies here who got it, too, but I don't live in the Tucky part of the state.

Where’s ‘tucky? I have a feeling that’s where they are.

AndyinPA wrote: ↑Thu Oct 14, 2021 2:55 pm

pipistrelle wrote: ↑Thu Oct 14, 2021 2:50 pm

AndyinPA wrote: ↑Thu Oct 14, 2021 12:15 am

I know more than a few trumpies here who got it, too, but I don't live in the Tucky part of the state.

Where’s ‘tucky? I have a feeling that’s where they are.

Tucky is in the red part of the state; i.e., not Pittsburgh, Philadelphia, Scranton, Erie, maybe Harrisburg. You know, like just about every other state, more of an urban/rural divide. Lots of territory, not so many people, although that's not necessarily true everywhere. The former guy seems intent on driving the suburban group to the Dems.

LM K wrote: ↑Tue Sep 28, 2021 3:56 pm

neonzx wrote: ↑Tue Sep 28, 2021 9:52 am What is wrong with these health care professionals? They want to expose those they are entrusted to care for? Find another line of work.

This has been a fascinating issue for me.

When the vax was released for healthcare workers, my sister was a bit hesitant to be vaccinated. She's a huge fan of vaccines. We are a vaxed family.

My sister has worked covid since the beginning. But the speed at which the vax was developed was of concern to her.

The hesitancy to try new meds is common amongst healthcare workers. What happens in the lab doesn't always match what happens when a drug enters the real world. Docs and nurses see what happens when someone reacts badly to a drug.

Lori returned to work from FMLA just before Christmas. Her first shift scared her. She told us "this isn't the covid we had in the spring". She got her first jab the next day.

I found her concerns valid. I shared the same concern. I decided to get vaxed asap because, as a scientist, trust science. And I wanted my life back.

I understand vaccine hesitancy amongst healthcare professionals. But MANY antivaxxers hide as vaccine hesitant. Vax mandates have shown us whom is hesitant and whom is antivax.

Houston Methodist Hospital was the first hospital to mandate vaccines for all healthcare workers. A group of 117 nurses sued the hospital to stop vax mandate and keep their job.

The lead plaintiff claimed to be vax hesitant. She's not. When asked during an interview when she would be comfortable getting the covid vax, her answer was something like 10 years in the future. After all, the vax is really new. AND she was fighting for her freedumbs.

The minute a covid vax "hesitant" adds a second excuse for why they're not getting vaxed, it's obvious that they're not hesitant. They're antivax.

RVInit wrote: ↑Fri Oct 15, 2021 12:34 pm Am I wrong in the impression that because we already had coronaviruses in the past and also SARS that the vaccine development for Covid-19 wasn't really entirely from scratch? That much of the study and information that is required to develop a vaccine was already known, at least somewhat and that is why it didn't take the normal 10 years? I can't remember where I got that information from, but honestly, I'm operating on zero sleep right now and may be hallucinating.

The hesitancy to try new meds is common amongst healthcare workers. What happens in the lab doesn't always match what happens when a drug enters the real world.

bill_g wrote: ↑Fri Oct 15, 2021 9:03 am On NPR yesterday afternoon: TX and FL have passed, or will pass, laws making it illegal for local govts and employers to mandate employee vax, and TX added the right for employees to sue their employers if terminated. One TX county has already been assessed fines ranging in the millions for mandating county employees be vax'd.

Sorry. No citation for either.

Uninformed wrote: ↑Fri Oct 15, 2021 10:42 am “Florida fines key county $3.5 million for mandating vaccines”:
https://www.pbs.org/newshour/politics/f ... g-vaccines

Slim Cognito wrote: ↑Fri Oct 15, 2021 2:38 pm

Uninformed wrote: ↑Fri Oct 15, 2021 10:42 am “Florida fines key county $3.5 million for mandating vaccines”:
https://www.pbs.org/newshour/politics/f ... g-vaccines

Now what? Say they decide not to pay? Can they take legal action to get the fines dropped?

I still don't see this bringing suburban housewives and moms back to the GOP fold.

RVInit wrote: ↑Fri Oct 15, 2021 12:34 pm
Am I wrong in the impression that because we already had coronaviruses in the past and also SARS that the vaccine development for Covid-19 wasn't really entirely from scratch? That much of the study and information that is required to develop a vaccine was already known, at least somewhat and that is why it didn't take the normal 10 years? I can't remember where I got that information from, but honestly, I'm operating on zero sleep right now and may be hallucinating.

In late 1987, Robert Malone performed a landmark experiment. He mixed strands of messenger RNA with droplets of fat, to create a kind of molecular stew. Human cells bathed in this genetic gumbo absorbed the mRNA, and began producing proteins from it1.

Realizing that this discovery might have far-reaching potential in medicine, Malone, a graduate student at the Salk Institute for Biological Studies in La Jolla, California, later jotted down some notes, which he signed and dated. If cells could create proteins from mRNA delivered into them, he wrote on 11 January 1988, it might be possible to “treat RNA as a drug”. Another member of the Salk lab signed the notes, too, for posterity. Later that year, Malone’s experiments showed that frog embryos absorbed such mRNA2. It was the first time anyone had used fatty droplets to ease mRNA’s passage into a living organism.

Those experiments were a stepping stone towards two of the most important and profitable vaccines in history: the mRNA-based COVID-19 vaccines given to hundreds of millions of people around the world. Global sales of these are expected to top US$50 billion in 2021 alone.


By the late 2000s, several big pharmaceutical companies were entering the mRNA field. In 2008, for example, both Novartis and Shire established mRNA research units — the former (led by Geall) focused on vaccines, the latter (led by Heartlein) on therapeutics. BioNTech launched that year, and other start-ups soon entered the fray, bolstered by a 2012 decision by the US Defense Advanced Research Projects Agency to start funding industry researchers to study RNA vaccines and drugs. Moderna was one of the companies that built on this work and, by 2015, it had raised more than $1 billion on the promise of harnessing mRNA to induce cells in the body to make their own medicines — thereby fixing diseases caused by missing or defective proteins. When that plan faltered, Moderna, led by chief executive Stéphane Bancel, chose to prioritize a less ambitious target: making vaccines.


That initially disappointed many investors and onlookers, because a vaccine platform seemed to be less transformative and lucrative. By the beginning of 2020, Moderna had advanced nine mRNA vaccine candidates for infectious diseases into people for testing. None was a slam-dunk success. Just one had progressed to a larger-phase trial.

But when COVID-19 struck, Moderna was quick off the mark, creating a prototype vaccine within days of the virus’s genome sequence becoming available online. The company then collaborated with the US National Institute of Allergy and Infectious Diseases (NIAID) to conduct mouse studies and launch human trials, all within less than ten weeks.

BioNTech, too, took an all-hands-on-deck approach. In March 2020, it partnered with New York-based drug company Pfizer, and clinical trials then moved at a record pace, going from first-in-human to emergency approval in less than eight months.

While only 3 small interfering RNA (siRNA)-based therapies have been approved (patisiran, givosiran, and lumasiran), there are 7 other candidates in phase 3 trials. A review published in Biochemical Pharmacology provided an overview of siRNA therapeutics as they are poised to become a “standard modality of pharmacotherapy.”

RNA interference is a natural mechanism by which eukaryotic cells control gene activity. siRNAs cause targeted gene suppression and allow therapies to target and silence the messenger RNA products of genes, the authors noted.

Creating siRNA-based drugs has been a 20-year process, but in 2018, the FDA approved patisiran, the first siRNA, to treat hereditary transthyretin amyloidosis (hATTR); in 2019, givosiran was approved to treat acute hepatic porphyria; and in 2020, lumasiran was approved to treat primary hyperoxaluria type 1.

raison de arizona wrote: ↑Fri Oct 15, 2021 2:41 pm

Slim Cognito wrote: ↑Fri Oct 15, 2021 2:38 pm

Uninformed wrote: ↑Fri Oct 15, 2021 10:42 am “Florida fines key county $3.5 million for mandating vaccines”:
https://www.pbs.org/newshour/politics/f ... g-vaccines

Now what? Say they decide not to pay? Can they take legal action to get the fines dropped?

I still don't see this bringing suburban housewives and moms back to the GOP fold.

Well I would expect that they can (and will) certainly sue, but I don't think they can decide not to pay. The state will just deduct the fines from the money they send the counties, is my understanding.