Schizophrenia

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Tiredretiredlawyer
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Schizophrenia

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https://www.theguardian.com/science/202 ... cell-links
Schizophrenia study finds evidence of reduced links between brain cells
Pioneering research on living patients could pave way for new and better treatment

Prof Oliver Howes from the MRC London Institute of Medical Sciences, Imperial College London and King’s College London, who led the study, said: “Our current treatments for schizophrenia target only one aspect of the disease: the psychotic symptoms.

“But the debilitating cognitive symptoms, such as loss of abilities to plan and remember, often cause much more long-term disability and there’s no treatment for them at the moment.”

The study, published in Nature Communications, focused on measuring a protein found in synapses called SV2A, which has been shown to be a good marker of the overall density of connections in the brain.

They found that levels of SV2A were significantly lower in the front of the brain – the region involved in planning – in people with schizophrenia.
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