Hijack this thread

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p0rtia
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Re: Hijack this thread

#26451

Post by p0rtia » Thu Jun 13, 2019 2:41 pm

Hurtzi wrote:
Thu Jun 13, 2019 7:24 am
So I guess you know what you are talking about.

I do as well, having my experiences with binge eating for nearly 60 years now.

Maybe pOrtia will start a thread as proposed by herself.

Ps:
This post is an answer to Roadscholar and not Foggy
I'm waffling, I admit. I'm just not sure I want to take it on. Yes, I know I would have no actual duty to respond to posts repeating destructive stereotypes, but this is a topic I care passionately about, so I would want to. Do I have time for that? And the psychic energy? Because the truth is I get angry when I hear the ignorance and the superiority, even from friends. :heart:

What I really wanted was a thread to discuss the very cool weight management info that is coming to a boil these days: Not only IF and its cousins, but the hormonal approach (featuring insulin resistance/response), and what I believe to be the horribly destructive "low fat" protocol we've been fed for the past fifty years. I so appreciate the brains here, and it is such an interesting subject.

Is that possible?

Oh, and hey there, Hurtzi! :bighug: Sixty years beats my 40. It's been four years since became a binge-er in remission, as I like to call it, but once a binge-er always a binge-er, at least in the head.
No matter where you go, there you are! :towel:
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Re: Hijack this thread

#26452

Post by p0rtia » Thu Jun 13, 2019 2:44 pm

ZekeB wrote:
Wed Jun 12, 2019 7:06 pm
Maybenaut wrote:
Mon Jun 10, 2019 6:13 pm
:bored: Waited around all day for a repairman...
When I was in Italy and the repairman said domani, he meant two or three days. If he said dopodomani he meant two or three months.
I got back up to my sweet cabin in Upstate NY on June 3rd, and, being so amazingly competent, had arranged to have my phone and internet turned on June 1.

Over ten phone calls and five-plus hours on the phone with Verizon later: I got internet restored on June 6, and am still waiting for long-distance phone service (today is June 13). Let me check to see if it is back on ... Nope.

:madguy: :madguy: :madguy: :madguy: :madguy: :madguy: :madguy:
No matter where you go, there you are! :towel:
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Re: Hijack this thread

#26453

Post by Maybenaut » Thu Jun 13, 2019 3:28 pm

I cancelled my repairman at 6:00 when he didn't show.

Then I published a Yelp! review, giving him a 1-star, calling him a "complete no-show," and describing what happened. Within 30 seconds of hitting the send button on Yelp, my phone rang. Pretty sure he gets notified when he gets a Yelp review. I declined to answer.

Then this morning he sent me a text asking to reschedule for Saturday, said he'd do the work for free. I said no thanks.
"Hey! You know, we left this England place because it was bogus. So if we don't get some cool rules ourselves, pronto, we'll just be bogus too." - Thomas Jefferson

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Re: Hijack this thread

#26454

Post by tek » Thu Jun 13, 2019 4:02 pm

:like:

Fool me once, etc..
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Re: Hijack this thread

#26455

Post by Danraft » Thu Jun 13, 2019 5:10 pm

p0rtia wrote:
Thu Jun 13, 2019 2:41 pm
Hurtzi wrote:
Thu Jun 13, 2019 7:24 am
So I guess you know what you are talking about.

I do as well, having my experiences with binge eating for nearly 60 years now.

Maybe pOrtia will start a thread as proposed by herself.

Ps:
This post is an answer to Roadscholar and not Foggy
I'm waffling, I admit. I'm just not sure I want to take it on. Yes, I know I would have no actual duty to respond to posts repeating destructive stereotypes, but this is a topic I care passionately about, so I would want to. Do I have time for that? And the psychic energy? Because the truth is I get angry when I hear the ignorance and the superiority, even from friends. :heart:

What I really wanted was a thread to discuss the very cool weight management info that is coming to a boil these days: Not only IF and its cousins, but the hormonal approach (featuring insulin resistance/response), and what I believe to be the horribly destructive "low fat" protocol we've been fed for the past fifty years. I so appreciate the brains here, and it is such an interesting subject.

Is that possible?

Oh, and hey there, Hurtzi! :bighug: Sixty years beats my 40. It's been four years since became a binge-er in remission, as I like to call it, but once a binge-er always a binge-er, at least in the head.
It's a fascinating area, and we are just now getting to the real centers.
For ages scientific research, especially cancer, focussed on DNA that coded for proteins and call everything else "junk" DNA. It was an absurd idea considering that meant 92%-98% of the chromosomes did nothing. Now, it is generally accepted it manufactures the RNA regulatory machinery that is often referred to as epigenetics. As an evolutionary molecular biology guy with degrees in the 80's, almost nothing even vaguely resembles what was taught then.

The academic inertia is still a restraint, but in my view, this is why the 30 year War on Cancer hasn't won many battles. At the heart of the metabolic disease family is epigenetics with very strong indications that early epigenetic markers (even during pregnancy ) can have effects decades later.

One area I became aware of, because of a friend asking me to look at traumatic head injury treatments, was some studies on Tibetan Sherpas and their high altitude adaptation. They have some SNP's that I had seen in Fibromyalgia's global-wide-association-studies. The Sherpas' children express diabetes at very different rates as well, and it appears related to peroxide genes (PPAR ) activated by the endoplasmic reticulum's Integrated Stress Response system that is involved in the Unfolded Protein Response (think Alzheimer's) and the area that modulates pain adaptation (think Fibromyalgia) invoking the only place the 23rd Amino Acid (yes, we are taught 20...), Hypusine, is used in translational regulation. Altered tRNA and ribosomes produce different sets of protein than normal (from the same coding).

This is evolutionarily conserved from eukaryotes in response to changes in environment, and this set is hypoxia and cold shock related.(in fact cold water immersion can cause high altitude adaptions response).
But, across the board in diabetes--(gestational, DBII, etc ) this Elf factor is involved.

I don't know how true this is, but it seems we are finally poised for some medical progress after long stagnation.

Vaccines, antibiotics, and surgery (trauma care) are great, but there has been, no offense to anyone, less than remarkable progress elsewhere. And, I just want rap my shoe on the table and wake all the different research disciplines up, with the big pharma honchos present (skipping a nail manicure- no offense to well groomed men), and point out exhibits A,B, C, D, etc, explain "Streetlight Effect," and say, "Look where the keys are!" to finally make some research money go where it so obviously would give enormous benefits.

And, there's existing FDA approved medications with off label uses.
For Fibromyalgia, some studies have shown Metformin to have 60% -80% reduction in pain and tender spots at 4 weeks on. For these poor souls the phrase "There's no cure for that." Is not only disheartening, but I believe it's wrong.

Tricky? Yes.
But we know where the epigenetic markers are now and need to reset them-- demethylate them on a selective basis. It is known how to do this in a less selective manner, but that is reckless and has potentially large negative consequences.
With CRISPr, and the unique amino acid and pathways, narrowing this down to a drug target could be a game changer in ALL chronic diseases-- even those like Parkinson's and Huntington's and Lupus which have strong genetic associations (but only express later in life).

But, no one has the time to read all this barrage of info with regular time demands. I barely have a grip on it, and I've reviewed over 3000 papers.
Speaking of which, the one's I've marked as important (by no real system), I have in a sortable spreadsheet and there's 300 or so relevant Fibromyalgia.

I really haven't gone into the glycoproteins (gehrlin, lepton, etc) as that's one I want to wrap together with the endocannabinoids( and an evolution of regulatory systems hypothesis that's rumbling around ), but there are a hundred or so of those (the spread sheet is 5600 lines but it boils down to around 2000).

I can't claim anything of value to it, except its the path my " latent inhibition" semi-schizophrenic brain took. I can cloud-share a search on a topic if wanted. I haven't checked it thoroughly to be assured that a google search for "Lesbian Midget Nuns" hasn't slipped through the filters, and I don't want to embarrass my parrots with whom I share the computer (that's my story and I'm sticking to it).

And, regarding all the opinions. We are all wrong. The objective is to be "less wrong" tomorrow.
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Re: Hijack this thread

#26456

Post by Hurtzi » Thu Jun 13, 2019 5:21 pm

I found porn videos with midget lesbians and with midget nuns. None with midget lesbian nuns. Sad.
The "water bear" is the first creature to live on the moon.

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Re: Hijack this thread

#26457

Post by p0rtia » Thu Jun 13, 2019 8:52 pm

Cool ramble, Danraft. I know just enough about genetics and biology to follow what you're saying (without ever dreaming of adding anything substantive to the discussion). Though I did find myself telling my ENT doc on Wednesday, as we discussed IF and low carb and he expressed his concern that if he didn't eat enough carbs, his muscles wouldn't get enough glucose, that he had nothing to fear because first of all, there was more than enough glycogen in the liver to carry him through a day or so, and that secondly, the bod produces plenty of glucose from amino acids, lactate, and lipids when fasted. I'm sure I screwed up the details, though :cantlook:

Your fibro talk makes me want to rush out and get a dear friend (who suffers horribly from fibro but alas is not diabetic) on metformin.

What's your take on cancer as a metabolic process, in whole or in part?
No matter where you go, there you are! :towel:
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Re: Hijack this thread

#26458

Post by RTH10260 » Thu Jun 13, 2019 10:44 pm

A possible mishap in the last days of the Obama adminstration sends the far rightwingers internet publications into a craze. They say that Obama was trying to hide missteps during his eight years. As if any significant events would not be recorded elsewhere but only on the WH government public server. :brickwallsmall: :doh:
Removal of ICE Speeches Collection Demonstrates Weaknesses in Federal Agencies’ Archiving Practices
by Sarah John JUN 11, 2019 5:03 AM

In the dying minutes of the Obama administration’s final term, Immigration and Customs Enforcement (ICE) removed from its website a collection of almost 200 speeches and testimonies delivered by agency leadership dating back to 2004. With a couple of clicks of a mouse, access to a federal government web resource containing 12 years of primary source materials on ICE’s history was lost. In our most recent report, the Web Integrity Project (WIP) documents the removal of this collection.

As our report details, a collection of 190 transcripts of speeches and testimonies hosted on the ICE website’s “Speeches and Testimonies” page was removed between the early afternoon of January 18 and late evening on January 19, 2017. (Compare the Internet Archive’s Wayback Machine captures from January 18, 2017 and on January 19, 2017.) The transcripts were of speeches and testimony delivered between 2004 and 2017 by high-ranking ICE officials, including the director of the agency and directors of ICE sub-units. Most contained prepared remarks submitted to congressional committees, often on controversial topics like the standard of medical treatment for detainees, treatment of unaccompanied children, sanctuary cities, drug trafficking, and E-Verify.

Testimony from Thomas Homan, who was appointed Acting Director of ICE by President Trump soon after inauguration in January 2017, featured prominently in the removed collection. In one removed transcript — a February 2016 statement to the Senate Judiciary Committee about the “Unaccompanied Children Crisis” — then-Executive Associate Director of Enforcement and Removal Operations Homan detailed how ICE contracted out to “effectuate” the transportation of “UC” and enumerated the “important steps” that the administration had taken to “deter illegal immigration.” In another removed transcript from May 2016, Homan detailed how local jurisdictions “limiting or declining cooperation with ICE” put “the public at risk.” It is not inconceivable that an outgoing Democratic administration might want to avoid preserving these public stances for future scrutiny.


https://sunlightfoundation.com/2019/06/ ... ollection/

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Re: Hijack this thread

#26459

Post by Foggy » Fri Jun 14, 2019 7:14 am

Yesterday we got a new roof. Kitteh Nightmare. Sounded like 12' tall Godzilla Squirrels From Hell up there. They give 'em boppers - big rubber mallets for SMASHING the roof. At lunch hour, they ate sammiches with one hand and kept SMASHING with boppers in the other hand. These guys go home, their wives are cooking dinner, and they're SMASHING their own houses with boppers. That's just how they live. :blink:
Any time my questions are all fully answered, I know I'm asking the wrong questions. - Bernard Samson

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Re: Hijack this thread

#26460

Post by kate520 » Fri Jun 14, 2019 11:51 am

As you may remember, we moved in December to Pomona. :shock: Just saying ‘Pomona’, if you live in SoCal, conjures up images of biker gangs, Mexican gangs, drugs, guns. May have been true once, but it isn’t now. It’s relatively peaceful in most parts, and where we live it’s positively bucolic. We’re Surrounded by Bonelli Regional Park, Brackett Airfield and Fairplex (acres of county fair space, trade show buildings, barns and a drag strip). The Claremont Colleges are 15 mins away. I’m loving it.

We’re in a quarantine area for chickens, though. Sorry, boss, you can’t visit until further notice. :mrgreen: Virulent Newcastle is the disease. No feed stores have chicks, no internet chicken store can sell eggs or chicks to this area. I was sad; we’re down to two hens, one of whom is old and has nearly stopped laying. Then a friend called, and now I have 6 3-month olds! I probably shouldn’t have accepted them, I’m kind of a rule follower when the rule is for health and safety of animals, but I’d checked the maps. Pomona was very near ground zero for the epidemic which began March 2018, and hasn’t had a new case since, and Monrovia, where the chicks came from, has never had a case. Two are bantams.

The skunks we evicted from under the house have held no grudge, still come every night for grubs but now they have 🤗 babies. OMG baby skunks are adorable!! There is one who squirms through the holes in the chicken coop fencing and grazes their leftovers around 6:30 every evening. The first time the girls were alarmed and very quiet. Now, they all graze together. No spraying so far. I went in last night to clean up and it never looked up, just casually moved to the far side of the coop. This makes me unreasonably happy.

There is, however, trouble in paradise. We’re next to Ganesha Park, established in 1917, very large and well-used by families. There’s a community pool - and homeless encampments in the hills. The city has an abandoned building they’ve turned into a decent, air conditioned shelter, and has been rounding them up from the park now that summer, and kids, are here. There is one contingent that doesn’t want to leave — the tweakers.

One man in particular who is personable and approachable when sober and a monster when tweaked - Tim - has been terrorizing some owners on the other side of the hill from us (thank god). He likes to take his clothes off. He has a pretty impressive member, apparently, as it’s usually the first thing mentioned in the NextDoor posts. :lol: But he also likes to light fires, peep through plate glass windows with his impressive member, en guarde, pressed up against the window while people are watching tv, and attack older men who try to protect themselves. The neighbors have formed a kind of posse and they take turns making sure they know where he is on any given day. Yesterday he exposed himself to some children in the park, so I expect he’ll be in jail soon.

Tweakers aside, if you find yourself in SoCal in need of dinner or a place to stay or whatever, hit me up. I’d love to see you.
DEFEND DEMOCRACY

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Re: Hijack this thread

#26461

Post by Estiveo » Fri Jun 14, 2019 12:18 pm

Nope, nope, nope...

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Re: Hijack this thread

#26462

Post by Maybenaut » Fri Jun 14, 2019 1:02 pm

:o :shock: :eek2:

And to think people pay actual, real money to do that.

:fingerwag: :talktothehand: :nope:
"Hey! You know, we left this England place because it was bogus. So if we don't get some cool rules ourselves, pronto, we'll just be bogus too." - Thomas Jefferson

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Re: Hijack this thread

#26463

Post by Estiveo » Fri Jun 14, 2019 2:18 pm

IKR?
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Re: Hijack this thread

#26464

Post by Sunrise » Fri Jun 14, 2019 6:12 pm

That’s really and truly FAKE NEWS! I was so terrified I checked it out. The Gyro Drop is a real thing but the fast drop is just a speeded up shot. :swoon:
"I am no longer accepting the things I cannot change. I am changing the things I cannot accept."
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Re: Hijack this thread

#26465

Post by tek » Fri Jun 14, 2019 6:43 pm

CIAGa.jpg
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There's no way back
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Re: Hijack this thread

#26466

Post by Estiveo » Fri Jun 14, 2019 7:13 pm

Sunrise wrote:
Fri Jun 14, 2019 6:12 pm
That’s really and truly FAKE NEWS! I was so terrified I checked it out. The Gyro Drop is a real thing but the fast drop is just a speeded up shot. :swoon:
Well, that's a relief. And slowing it down, reducing the height, and eliminating the bungees takes it from 3 nopes to...let's see...carry the 2 and allow for windage...hmmm...

Whaddaya know? Still a triple nope.
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Re: Hijack this thread

#26467

Post by Tiredretiredlawyer » Fri Jun 14, 2019 8:15 pm

Here’s a big NOPE to even watching the video! :eek2: :sick:
A 19th Amendment Centennial Moment: African-American Naomi Anderson was a leader in the suffrage movement in the west, a published poet, barber, community activist, and teacher.

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Re: Hijack this thread

#26468

Post by Sugar Magnolia » Fri Jun 14, 2019 8:47 pm

I would probably ride it twice. I love that sort of thing.

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Re: Hijack this thread

#26469

Post by RVInit » Sat Jun 15, 2019 7:46 am

I watched that video. My hands and feet immediately broke out in a sweat. Too much empathy? :think:
"I know that human being and fish can coexist peacefully"
--- George W Bush

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Re: Hijack this thread

#26470

Post by neonzx » Sat Jun 15, 2019 7:52 am

tek wrote:
Fri Jun 14, 2019 6:43 pm
CIAGa.jpg
I need that hat. Where to buy?
To which Trump replied, Fuck the law. I don't give a fuck about the law. I want my fucking money.

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Re: Hijack this thread

#26471

Post by p0rtia » Sat Jun 15, 2019 8:36 am

Day 15 since Verizon was supposed to reinstate my my phone/internet services, and I still have no long-distance service. Three representatives (among the ten or so I've spoken with) have set up renewal of services three times, with me three times going through the Automated Third Party Confirmation system that is hell on wheels and doesn't understand me when I say "Yes" so must repeat the question. This because now I am not "reinstating" services, I am "adding" services because oh well, that's the system. Several representatives have spouted gibberish after getting very confused by the trail of mayhem that has been created. I have been told twice that my problem has been solved by technicians in the field--by text message. I have been told that the order has not gone through, that the order was mysteriously cancelled (blame laid on the hellish automated Third Party Confirmation), and, repeatedly, that the order will happen any second now. The Verizon Executive Grievance number rings twice and then gives a busy signal (I can call 800 numbers).

This is why private citizens should not be allowed to keep handguns and ammo in the home.

:50caliber: :machinegun: :flame:
No matter where you go, there you are! :towel:
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Re: Hijack this thread

#26472

Post by tek » Sat Jun 15, 2019 2:20 pm

neonzx wrote:
Sat Jun 15, 2019 7:52 am
tek wrote:
Fri Jun 14, 2019 6:43 pm
CIAGa.jpg
I need that hat. Where to buy?
Not sure, I got the pic from my daughter... I'll ask her..
There's no way back
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Re: Hijack this thread

#26473

Post by neonzx » Sat Jun 15, 2019 10:39 pm

Oi.
Because there are collectively at Fogbow the way smartest people, I'm sure you will have the answer for this.

A friend bought this yesterday at a thrift/Goodwill/charity type store. $6.00

Image

It's old. It's solid wood construction and the size of a bed nightstand. The front door tilts out to reveal a removable steel container. And I can't determine the original function. My friend said "maybe it was storing flour or kitty litter (cat person)". I said no, it's not for food or cat litter.

The best guess I have is to was to put ashes from a fireplace for later disposal? :confused:

p.s. He bought it for his patio so he would have a place to set his beers so his cat would stop knocking them over. :rotflmao:
To which Trump replied, Fuck the law. I don't give a fuck about the law. I want my fucking money.

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Re: Hijack this thread

#26474

Post by RTH10260 » Sat Jun 15, 2019 10:57 pm

neonzx wrote:
Sat Jun 15, 2019 10:39 pm
Oi.
Because there are collectively at Fogbow the way smartest people, I'm sure you will have the answer for this.

A friend bought this yesterday at a thrift/Goodwill/charity type store. $6.00



It's old. It's solid wood construction and the size of a bed nightstand. The front door tilts out to reveal a removable steel container. And I can't determine the original function. My friend said "maybe it was storing flour or kitty litter (cat person)". I said no, it's not for food or cat litter.

The best guess I have is to was to put ashes from a fireplace for later disposal? :confused:

p.s. He bought it for his patio so he would have a place to set his beers so his cat would stop knocking them over. :rotflmao:
I know such contraptions form restaurants. From the time where smoking was allowed, of course. The waiter/waitress would collect the ashtrays and drop the contents into the tin box, clean the ashtray and return it to the table. The tin would be the safe in case some remaining sparks were to smolder on whatever else was in the box.

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Re: Hijack this thread

#26475

Post by neonzx » Sun Jun 16, 2019 12:58 am

RTH10260 wrote:
Sat Jun 15, 2019 10:57 pm
I know such contraptions form restaurants. From the time where smoking was allowed, of course. The waiter/waitress would collect the ashtrays and drop the contents into the tin box, clean the ashtray and return it to the table. The tin would be the safe in case some remaining sparks were to smolder on whatever else was in the box.
Hm. Well that makes sense -- I was on the right track thinking it was for ashes, but wasn't think of dumping ashtrays. I worked in food service as well but we never had any fancy bins to clear ashtrays. As such, we occasionally would have trash can fire incidents.

Thanks for helping solve the mystery. I took those photos and said I would find the answer. Or, I said he could wait until Antique Road Show was in the area and take to them. Maybe his $6.00 purchase is worth a whole lot more. :dance:
To which Trump replied, Fuck the law. I don't give a fuck about the law. I want my fucking money.

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