Dementia and Alzheimer's

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Tiredretiredlawyer
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Dementia and Alzheimer's

#1

Post by Tiredretiredlawyer »

http://www.latimes.com/science/sciencen ... story.html
Is it Alzheimer’s or another dementia form? Why doctors need to distinguish and how they might do so

Newly unveiled research results are bringing some clarity to such deliberations. And other new research, published Wednesday in the journal Neurology, proposes a new diagnostic tool that may be able to detect Alzheimer’s, and distinguish it from another form of dementia, more simply and cheaply than does the best test now available.

At the Alzheimer’s Assn. International Conference in London last week, researchers reported their preliminary findings from a trial that is testing the impact of diagnostic testing for Alzheimer’s disease on nearly 19,000 Medicare beneficiaries. After getting the results of a PET brain scan to detect and measure amyloid deposits, which are the key hallmark of Alzheimer’s disease, roughly two-thirds of the subjects saw their medication regimens changed or were counseled differently by their doctors about what to expect.

A second study presented in London analyzed data from several studies, and found that in a large population of research participants with cognitive concerns, brain amyloid PET scans led to a change in diagnosis in approximately 20% of cases.

“People should know what’s coming,” said Dr. Maria Carrillo, chief science officer for the Alzheimer’s Assn. The Centers for Medicare & Medicaid Services has given amyloid scans a provisional approval, meaning they do not routinely pay for them. The results may guide the agency to rethink its position, she added.
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Re: Dementia and Alzheimer's

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Post by Fortinbras »

As I hit age 70 I worry about becoming senile and demented (yes, I know most of you think I've already passed that milestone). When I was a little boy and fluoroscopes were considered leading edge, we never heard the word 'Alzheimer's' - just senility. Now it seems there are different ways of losing one's mind in old age ... but it's not really clear how to tell them apart, at least until the patient is dead and they open his skull.

The odd thing is that the elderly senile don't seem to get excited about having forgotten important information. When we are in our prime, we get concerned about "I just had it on the tip of my tongue", but somehow the elderly will tell you calmly they can't remember their birthdates or their children's names and they aren't the least upset about it.

If someone knows some simple way of distinguishing different forms of dementia, please explain them to us.
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Re: Dementia and Alzheimer's

#3

Post by Slim Cognito »

Not a doctor but did transcription for 30 years. There's Alzheimer's, there's confusion caused by a bad mix of prescription meds and that same confusion can also result from obstructed carotid arteries. First you try switching meds. If no improvement, you do a carotid artery scan. If that's normal enough, you assume it's Alzheimer's. Family history is helpful, if available.

I'm adopted, so no family history, and was having severe memory loss rather young, in my mid 50s. I talked to my doctor who didn't want to put me on any medication due to my youngish age so she advised me to start writing, specifically to write down what I've read. I'm a news junkie so I spend the mornings reading, then write entries in my *journal*, actually Facebook, summing up what I've read. It's done wonders for my memory. It also weeded out any "friends" who weren't on the same page as myself. It's a win-win.

Of course, I defer to anyone with an actual medical degree.

(Also too, I'm a gamer. With arthritis settling in, I had to trade in my agility-requisite games for puzzles. Every little bit helps.)
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Re: Dementia and Alzheimer's

#4

Post by Patagoniagirl »

Good observations Slim. I read a recent article cautioning those 65 and older using Benadryl as it sometimes causes dementia-type symptoms. IANAD but through personal experience I know that quite a few medical conditions also cause dementia/ALZ-type symptoms. Liver failure can also cause confusion when the liver fails to adequately eliminate excess ammonia from your system.

Best thing ever is to see your PCP and discuss all of the possibilities.
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Re: Dementia and Alzheimer's

#5

Post by Tiredretiredlawyer »

Fibromyalgia causes "fibro fog" which can easily be mistaken for early dementia. Fatigue from fibromyalgia can do the same. Combine fatigue and pain and fibro fog and you get reasons not to drive or sign important papers or tweet.
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Re: Dementia and Alzheimer's

#6

Post by Chilidog »

What does Trump have?

Edit:

He has both kinds. Country AND Western
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Re: Dementia and Alzheimer's

#7

Post by Tiredretiredlawyer »

Chilidog wrote:What does Trump have?

Edit:

He has both kinds. Country AND Western
:rotflmao:
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Re: Dementia and Alzheimer's

#8

Post by RoadScholar »

:thumbs:
The bitterest truth is healthier than the sweetest lie.
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Re: Dementia and Alzheimer's

#9

Post by Lani »

Extra-Virgin Olive Oil Preserves Memory and Protects Brain Against Alzheimer's Disease, New Research at Temple Shows

https://medicine.temple.edu/news/extra- ... isease-new
The Mediterranean diet, rich in plant-based foods, is associated with a variety of health benefits, including a lower incidence of dementia. Now, researchers at the Lewis Katz School of Medicine at Temple University (LKSOM) have identified a specific ingredient that protects against cognitive decline: extra-virgin olive oil, a major component of the Mediterranean diet. In a study published online June 21 in the Annals of Clinical and Translational Neurology, the researchers show that the consumption of extra-virgin olive oil protects memory and learning ability and reduces the formation of amyloid-beta plaques and neurofibrillary tangles in the brain – classic markers of Alzheimer's disease.

The Temple team also identified the mechanisms underlying the protective effects of extra-virgin olive oil. “We found that olive oil reduces brain inflammation but most importantly activates a process known as autophagy,” explained senior investigator Domenico Praticò, MD, Professor in the Departments of Pharmacology and Microbiology and the Center for Translational Medicine at LKSOM. Autophagy is the process by which cells break down and clear out intracellular debris and toxins, such as amyloid plaques and tau tangles.

“Brain cells from mice fed diets enriched with extra-virgin olive oil had higher levels of autophagy and reduced levels of amyloid plaques and phosphorylated tau,” Dr. Praticò said. The latter substance, phosphorylated tau, is responsible for neurofibrillary tangles, which are suspected of contributing to the nerve cell dysfunction in the brain that is responsible for Alzheimer's memory symptoms.
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Re: Dementia and Alzheimer's

#10

Post by ZekeB »

I use the cheaper stuff for frying. I wonder if that stuff works.
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Re: Dementia and Alzheimer's

#11

Post by Lani »

I did a lot of reading on this after the report appeared. The beneficial properties are only found in olive oil and can be reduced or destroyed by frying. 100% extra virgin cold pressed olive oil, taken by spoon, mixed into already cooked sauces, or drizzled on bread, salad, veggies, etc.

Olive oil was already being used with some good documentation for lowering cholesterol and the risk of heart disease.
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Re: Dementia and Alzheimer's

#12

Post by Lani »

Some info on fake extra virgin olive oil on the market.

The Truth About Extra-Virgin Olive Oil

It's come to light that many producers in Italy, the world's biggest importer of olive oil, have been cutting their oil with refined olive oil (lower-quality oil that has been treated with chemicals to mask imperfections) imported from Spain, Greece, or other countries, or even with soybean or other cheap oils, while others add flavors and colorants to cheap vegetable oil to make it resemble olive oil, and then sell this doctored oil as "extra-virgin olive oil" for export. In doing so, they've really undermined themselves in two ways: first, by flooding the market with fake "extra-virgin" olive oil, they've lowered the price -- and their profits.

Second, they've confused the palates of many consumers who now do not know what true extra-virgin olive oil tastes like, or which labels to believe. A 2010 study by researchers at the University of California, Davis, found that 69 percent of imported olive oil samples failed to meet the minimum standards for "extra-virgin" labeling in an expert taste and smell test.
:snippity:

As a result, two class-action lawsuits have been filed against Filippo Berio and Bertolli, two of the brands which failed the tests, for false advertising.

In the U.K., The Telegraph reported that "four out of five" bottles of Italian extra-virgin olive oil were adulterated with lower-quality oil from other countries, while last year, the New York Times published an infographic, "Extra-Virgin Suicide," with facts and figures regarding extra-virgin olive oil fraud.
This is an older article. There are now some certification controls, but you need to read labels.
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Re: Dementia and Alzheimer's

#13

Post by AndyinPA »

Good info. I use a lot of extra-virgin olive oil on salads. I never use salad dressings, just a touch of olive oil and some type of vinegar. I'll have to watch for the labeling.
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Re: Dementia and Alzheimer's

#14

Post by Estiveo »

Why pay extra for Italian olive oil when California brands are perfectly yummy?
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Re: Dementia and Alzheimer's

#15

Post by DejaMoo »

Alzheimer's isn't the only disease causing dementia. There's also Lewy Body Dementia, which is second only to Alzheimer's in the number of persons afflicted. LBD is fairly difficult to diagnose and distinguish from Alzheimer's, usually requiring a specialist working in conjunction with the patient and caregiver. Getting an accurate diagnosis is critical because certain medications (Benadryl is one of them) can dramatically worsen symptoms and cause psychotic episodes.

There's a relationship between LBD and Parkinson's. As a rough guide, if the physical symptoms manifest first, it's usually diagnosed as Parkinson's. If the psychiatric symptoms manifest first, it's probably LBD.
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Re: Dementia and Alzheimer's

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Post by DejaMoo »

Estiveo wrote:Why pay extra for Italian olive oil when California brands are perfectly yummy?
Higher quality than the foreign oils, and much less likely to be adulterated/counterfeited.
I've heard this bull before.
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Re: Dementia and Alzheimer's

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Post by Lani »

The article I linked mentioned Trader Joe's olive oil.
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Re: Dementia and Alzheimer's

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Post by RoadScholar »

As having bona fide Extra Virgin, or the adulterated stuff?
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Re: Dementia and Alzheimer's

#19

Post by Lani »

RoadScholar wrote:As having bona fide Extra Virgin, or the adulterated stuff?
Bona fide, great taste, and not overpriced.
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Re: Dementia and Alzheimer's

#20

Post by AndyinPA »

Lani wrote:
RoadScholar wrote:As having bona fide Extra Virgin, or the adulterated stuff?
Bona fide, great taste, and not overpriced.
And my choice! :clap:
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Re: Dementia and Alzheimer's

#21

Post by ZekeB »

Is it still virgin if it was bottled near a volcano?
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Re: Dementia and Alzheimer's

#22

Post by kate520 »

That shocked me, to find that not one of TJs EVOO brands is pure. You know whose is? COSTCO!
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Re: Dementia and Alzheimer's

#23

Post by WriteItDown »

Hi

Another thing that can give you signs of dementia is chemotherapy as many of you unfortunately know. An extreme example: I was recently on one drug that affected my mentation horribly. About 3 days after getting it IV, I drove into the nearby town, did some shopping, stopped at a drive in to pick up a carry out lunch, started to drive home and awakened in a hospital 6 hours later. I got there by ambulance but have no memory of what happened except snipits of walking barefoot in a cold stream and reaching into the water for credit cards and other purse contents! Apparently I had driven home (10 miles) over winding roads, around a reservoir and eventually ended up in the front yard of one of my rural neighbors who called an ambulance. I had one shoe on and was missing the other and was soaking wet.

After 3 days and lots of diagnostics and lots of $ spent no reason for this was found, no stroke, heart attack, Alzheimer's or other signs of dementia :think: . So it had to be that someone slipped me a Mickey, I was abducted by aliens or the new drug. It took about 2 weeks to feel okay again but I am still freaked out a bit. It has not happened again. Whew...

Has anyone else had a similar experience? I am so glad that I did not kill anyone while I was driving. It is amazing how the brain can just go into autopilot. Yikes
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Re: Dementia and Alzheimer's

#24

Post by Sam the Centipede »

Scary story, WriteItDown, almost Twilight Zone. Glad it ended ok, and I share your horror at the possibility of finding that my Mr. Hyde had done deeds that my Dr. Jekyll would never have considered.*

I know little of dementia and similar conditions, but it is clear that a mountain of scientific knowledge is building, especially when compared with the ignorance of two decades or so back. People who know more than me say evidence is accumulating about possible ways (drugs, diet, lifestyle, etc.) to prevent, delay or mitigate these conditions :clap: ... but that good news is offset by the unhappy insight that any preventive treatment would need to start in a person's forties. So those of us in the second halves of our lives are not going to escape what's in store. :(

* Another reason why I don't want guns in my house: if they're not there, I can't do anything with them to myself or others that I would regret later, however mad, bad or sick I get.
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Re: Dementia and Alzheimer's

#25

Post by RTH10260 »

Off Topic
Lani wrote:Some info on fake extra virgin olive oil on the market.

The Truth About Extra-Virgin Olive Oil

:snippity:

This is an older article. There are now some certification controls, but you need to read labels.
recently in Italy:
Italy Arrests 33 Accused of Olive Oil Fraud
An Italian operation led to the arrest of 33 believed to be a part of the Piromalli clan, an organization that has allegedly infiltrated the olive oil trade in Italy and exported fake products to the U.S.
By MICHELLE SMITH on February 16, 2017

Italy’s Carabinieri arrested 33 suspects in the Calabrian mafia’s Piromalli clan, a criminal enterprise whose illicit dealings allegedly include exporting fake extra virgin olive oil to the United States.

About $42.8 million in assets were seized and charges filed against the suspects including mafia association, attempted murder, drug trafficking, money laundering and fraud, the police told the Investigative Reporting Project of Italy.

The Calabrian mafia, also known as the Ndràngheta, is believed to be the wealthiest, most powerful criminal network in Italy, and the Piromalli are believed to be a leading clan within that organization. In addition to drug trafficking, authorities believe they’re major players in agromafia, including an elaborate olive oil scheme.

According to investigators, the Piromalli were importing olive pomace oil, a product that’s extracted from already-pressed fruit pulp using chemical solvents, then labeling the low-quality, adulterated oil products as extra virgin olive oil and exporting it to the U.S. Those products were sold through retail chains in New York, Boston and Chicago, the IRPI revealed.


The Piromalli were capable of executing this scam because they have a grip on the right people in the right places, authorities allege. The clan is believed to control areas in and around the southern municipality of Gioia Tauro, including the region’s real estate, most of the food and agriculture businesses, and its strategically located port
https://www.oliveoiltimes.com/olive-oil ... raud/55364
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