Shortages of Medications

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Volkonski
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Shortages of Medications

#1

Post by Volkonski »

Consumers Struggle to Find EpiPens

https://www.nytimes.com/2018/05/10/well ... &smtyp=cur
On Wednesday, months after consumers around the country started reporting that they couldn’t purchase EpiPens to treat severe allergic reactions, the Food and Drug Administration announced there were shortages of two brands of epinephrine auto-injectors, including EpiPens, sold by the drug company Mylan, and Adrenaclick auto-injectors, made by Impax Laboratories.

:snippity:

The F.D.A. attributed the shortages to manufacturing problems, but the agency has not been able to provide any clear information or timeline about when the shortage will ease.

:snippity:

The shortage is not unique: dozens of drugs are on the F.D.A.’s list of medication shortages, including injectable anesthesia agents, pain medications, penicillin, feeding and hydration solutions, heart disease drugs, and even simple products like sterile water.
FDA's list of current drug shortages is here-

https://www.accessdata.fda.gov/scripts/ ... efault.cfm
Image“If everyone fought for their own convictions there would be no war.”
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Volkonski
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Re: Shortages of Medications

#2

Post by Volkonski »

A couple of months ago my primary care physician had to change my thyroid medication because of a shortage of the one I had been taking.

My new medication is derived from pigs so it is a good thing I have no religious objections to consuming pork products. It says "pork" in big letters right on the prescription bottle label to alter people who do have such objections.
Image“If everyone fought for their own convictions there would be no war.”
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Volkonski
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Re: Shortages of Medications

#3

Post by Volkonski »

In the interests of efficiency the manufacturers of just about everything have concentrated production in an ever smaller number of ever larger production facilities. This is why a fire that shut down half of one auto parts plant resulted in the shutdown of all Ford 150 and Chrysler Pacifica production.

It doesn't much matter if truck and van production is delayed a bit. Shortages of medications can result in deaths.
Image“If everyone fought for their own convictions there would be no war.”
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Re: Shortages of Medictions

#4

Post by Bill_G »

... suddenly Puerto Rico becomes important ...

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Volkonski
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Re: Shortages of Medications

#5

Post by Volkonski »

EpiPen shortage keeping some kids out of school

https://www.cbsnews.com/news/epipen-sho ... d=57926298
Eden Morris should be in kindergarten with his friends but the 5-year-old has been home since the school year started. Eden has severe allergies so Spanaway Elementary, about 35 miles south of Seattle, won't let him go to school without an EpiPen.

The U.S. is experiencing a shortage of the lifesaving device and parents are scrambling to find them because some schools won't let kids with allergies in the classroom if they don't have one. This affects as many as two students in every classroom in the U.S.

:snippity:

In a statement to CBS News, the Bethel School District said in part "our school nurses have been working with families throughout the EpiPen shortage to get students into school as quickly as possible." But Morris thinks the district should do more to help kids stay in school.

:snippity:

The EpiPen shortage is caused by manufacturing changes in response to FDA violations. It's so severe that in August, the FDA extended the expiration date for some EpiPens by four months.
Image“If everyone fought for their own convictions there would be no war.”
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Volkonski
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Re: Shortages of Medications

#6

Post by Volkonski »

Another critical medication now has only one supplier.

MD Anderson, Texas Children's scramble to cope with drug shortage

https://www.chron.com/local/prognosis/a ... witter.com
MD Anderson Cancer Center and Texas Children’s Hospital are scrambling to cope with the shortage of a critical drug used to treat most childhood cancers and for which there is no substitute.

The shortage of vincristine, which is deployed against leukemias, lymphomas and brain tumors, is rattling parents and the pediatric cancer-care community like no previous scarcity of a medication, say doctors. Some have been talking about rationing doses.

“This is truly a nightmare situation,” Dr. Yoram Unguru, a pediatric oncologist at the Herman and Walter Samuelson Children’s Hospital at Sinai in Baltimore, told the New York Times. “Vincristine is our water. It’s our bread and butter. I can’t think of a disease in childhood cancer that doesn’t use vincristine.”

:snippity:

The shortage was triggered when Teva Pharmaceutical Industries, one of two manufacturers of the drug, announced over the summer it was permanently halting production. That left Pfizer as the only manufacturer, but the mammoth pharmaceutical company has had snags ramping up its inventory, according to reports.
Image“If everyone fought for their own convictions there would be no war.”
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RTH10260
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Re: Shortages of Medications

#7

Post by RTH10260 »

this discusses some background issues in the pharmaceutical industry
How the Drug Industry Sacrifices Children With Cancer
The outrageous, contrived shortage of one of the most widely used generic cancer drugs, vincristine, reflects multiple policy failures.

BY ROBERT KUTTNER OCTOBER 18, 2019
https://prospect.org/health/how-the-dru ... th-cancer/

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Re: Shortages of Medications

#8

Post by RTH10260 »

While Teva made a decision to discontinue its manufacture of the cancer drug, the company said its business decision did not lead to a shortage. Kelley Dougherty, a spokesperson for Teva, told The Hill that the Israel-based company evaluated data from 2017 to assess the market need for vincristine.

At that time, the market share split was on average 85% brand and only 15% generic/Teva,” she said, according to The Hill. "Based on this information about usage and availability and an annual business assessment, Teva decided to discontinue the product, and alerted FDA of its decision in March 2019.”
in https://www.biospace.com/article/pfizer ... c-version/

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